Motif ID: NFY{A,B,C}.p2

Z-value: 2.639


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFYAchr6_+_411486650.811.2e-04Click!
NFYCchr1_+_40930062,
chr1_+_40930080		0.401.3e-01Click!
NFYBchr12_-_103055924-0.292.8e-01Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_38714111 4.542 NM_002687
 PNN
pinin, desmosome associated protein
chr17_+_44325127 4.518 NM_001002027
NM_005175
 ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr17_-_53950191 3.965 NM_004687
 MTMR4
myotubularin related protein 4
chr14_-_34001164 3.762 NM_138288
 C14orf147
chromosome 14 open reading frame 147
chr20_+_47096280 3.520 CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr4_+_166468266 3.435 NM_001017369
NM_006745
 SC4MOL

sterol-C4-methyl oxidase-like

chr14_+_23175383 3.356 NM_005794
NM_182908
 DHRS2

dehydrogenase/reductase (SDR family) member 2

chr2_-_71307705 3.330 NM_020459
 PAIP2B
poly(A) binding protein interacting protein 2B
chr6_+_26153590 3.316 NM_003531
 HIST1H3C
histone cluster 1, H3c
chr14_-_20807346 3.311 NM_001077442
NM_001077443
NM_004500
NM_031314
 HNRNPC



heterogeneous nuclear ribonucleoprotein C (C1/C2)



chr9_+_91115924 3.250 NM_001827
 CKS2
CDC28 protein kinase regulatory subunit 2
chr20_-_45418818 3.232 NM_012408
NM_183047
NM_183048
 ZMYND8


zinc finger, MYND-type containing 8


chr2_+_85676347 3.213 NM_016494
 RNF181
ring finger protein 181
chr1_+_144149794 3.103 NM_006472
 TXNIP
thioredoxin interacting protein
chr2_+_74539039 3.013 NM_012477
 WBP1
WW domain binding protein 1
chr14_+_23008723 2.972 NM_001042635
NM_015514
 NGDN

neuroguidin, EIF4E binding protein

chr2_+_198026470 2.922 NM_025147
 COQ10B
coenzyme Q10 homolog B (S. cerevisiae)
chr6_+_21701942 2.891 NM_003107
 SOX4
SRY (sex determining region Y)-box 4
chr12_+_56374004 2.746 NM_001017956
NM_001017957
NM_001017958
NM_006812
 OS9



osteosarcoma amplified 9, endoplasmic reticulum lectin



chr15_+_87919744 2.720 NM_152259
 C15orf42
chromosome 15 open reading frame 42

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 74 entries
enrichment   p-value GO term description
5.45 5.28e-07 GO:0006695 cholesterol biosynthetic process
4.87 2.11e-06 GO:0016126 sterol biosynthetic process
4.19 1.65e-12 GO:0006334 nucleosome assembly
4.02 3.57e-13 GO:0065004 protein-DNA complex assembly
3.98 1.36e-11 GO:0031497 chromatin assembly
3.89 6.45e-13 GO:0071824 protein-DNA complex subunit organization
3.88 1.63e-11 GO:0034728 nucleosome organization
3.55 8.78e-03 GO:0000819 sister chromatid segregation
3.51 2.58e-11 GO:0006323 DNA packaging
3.51 6.88e-04 GO:0000910 cytokinesis
3.43 1.93e-11 GO:0006333 chromatin assembly or disassembly
3.37 8.15e-06 GO:0000236 mitotic prometaphase
3.17 2.01e-06 GO:0007059 chromosome segregation
3.15 6.84e-10 GO:0071103 DNA conformation change
2.83 5.92e-04 GO:0006694 steroid biosynthetic process
2.82 4.79e-15 GO:0000087 M phase of mitotic cell cycle
2.71 2.34e-02 GO:0007088 regulation of mitosis
2.71 2.34e-02 GO:0051783 regulation of nuclear division
2.69 2.85e-19 GO:0000279 M phase
2.69 1.76e-12 GO:0000280 nuclear division

Gene overrepresentation in compartment category:

Showing 1 to 20 of 56 entries
enrichment   p-value GO term description
4.67 5.09e-11 GO:0000786 nucleosome
4.28 4.21e-02 GO:0000795 synaptonemal complex
3.45 3.23e-04 GO:0000794 condensed nuclear chromosome
3.33 7.05e-06 GO:0000779 condensed chromosome, centromeric region
3.30 2.14e-07 GO:0032993 protein-DNA complex
3.29 3.38e-05 GO:0000777 condensed chromosome kinetochore
3.14 8.12e-10 GO:0000793 condensed chromosome
3.03 3.55e-05 GO:0000776 kinetochore
2.83 8.66e-03 GO:0000922 spindle pole
2.74 1.03e-11 GO:0000785 chromatin
2.73 1.51e-06 GO:0000775 chromosome, centromeric region
2.59 5.55e-20 GO:0044427 chromosomal part
2.52 4.64e-22 GO:0005694 chromosome
2.41 2.82e-05 GO:0044454 nuclear chromosome part
2.37 2.16e-05 GO:0005819 spindle
2.14 2.59e-04 GO:0000228 nuclear chromosome
2.08 4.63e-04 GO:0005813 centrosome
1.99 6.28e-04 GO:0005759 mitochondrial matrix
1.92 1.58e-10 GO:0015630 microtubule cytoskeleton
1.84 8.22e-09 GO:0044429 mitochondrial part

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
9.99 6.97e-04 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
8.33 3.86e-02 GO:0016421 CoA carboxylase activity
1.37 6.32e-07 GO:0003677 DNA binding
1.31 2.49e-07 GO:0003676 nucleic acid binding
1.16 2.82e-06 GO:0005515 protein binding
1.10 1.17e-08 GO:0005488 binding